Murine CTLA4-IgG treatment inhibits airway eosinophilia and hyperresponsiveness and attenuates IgE upregulation in a murine model of allergic asthma.

Van Oosterhout, A J

Murine CTLA4-IgG treatment inhibits airway eosinophilia and hyperresponsiveness and attenuates IgE upregulation in a murine model of allergic asthma. [electronic resource] - American journal of respiratory cell and molecular biology Sep 1997 - 386-92 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1044-1549

10.1165/ajrcmb.17.3.2679 doi


Abatacept
Administration, Inhalation
Animals
Antigens, CD
Antigens, Differentiation--metabolism
Asthma--immunology
Bronchi--cytology
Bronchial Hyperreactivity--prevention & control
Bronchoconstrictor Agents--pharmacology
CTLA-4 Antigen
Cytokines--biosynthesis
Disease Models, Animal
Eosinophilia--immunology
Immunoconjugates
Immunoglobulin E--physiology
Immunoglobulin G--metabolism
Immunosuppressive Agents--metabolism
Male
Methacholine Chloride--pharmacology
Mice
Mice, Inbred BALB C
Ovalbumin--immunology
Protein Binding--immunology
Pulmonary Alveoli--cytology
Specific Pathogen-Free Organisms
Spleen--cytology
Up-Regulation