Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases. [electronic resource]
Producer: 19970731Description: 149-57 p. digitalISSN:- 0021-9738
- Animals
- CHO Cells
- Cell Cycle Proteins
- Cell Division -- drug effects
- Cell Line
- Cricetinae
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclin-Dependent Kinase Inhibitor p27
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Cyclins -- biosynthesis
- Cytomegalovirus
- Decorin
- Enzyme Inhibitors -- metabolism
- Extracellular Matrix Proteins
- Genetic Vectors
- HeLa Cells
- Humans
- Kinetics
- Lung
- Microtubule-Associated Proteins -- biosynthesis
- Proteoglycans -- biosynthesis
- Recombinant Proteins -- biosynthesis
- Skin
- Transfection
- Tumor Cells, Cultured
- Tumor Suppressor Proteins
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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