Topoisomerase II inhibitors induce DNA double-strand breaks at a specific site within the AML1 locus. [electronic resource]
Producer: 19970429Description: 490-6 p. digitalISSN:- 0887-6924
- Amsacrine -- pharmacology
- Antineoplastic Agents -- adverse effects
- Base Sequence
- Cell Line -- drug effects
- DNA Damage
- DNA, Neoplasm -- chemistry
- Dactinomycin -- pharmacology
- Doxorubicin -- pharmacology
- Etoposide -- pharmacology
- Genes, abl -- drug effects
- Humans
- Leukemia, Myeloid, Acute -- chemically induced
- Molecular Sequence Data
- Monocytes -- drug effects
- Restriction Mapping
- Topoisomerase II Inhibitors
- Translocation, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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