Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways. [electronic resource]
Producer: 19970314Description: 1562-71 p. digitalISSN:- 0270-7306
- Amino Acid Sequence
- Animals
- COS Cells
- DNA -- metabolism
- DNA-Binding Proteins -- metabolism
- Drosophila Proteins
- Drosophila melanogaster -- genetics
- Female
- Glutamic Acid -- genetics
- Janus Kinase 2
- Janus Kinases
- Leukemia, Experimental -- genetics
- Male
- Melanins -- analysis
- Mice
- Milk Proteins
- Molecular Sequence Data
- Neoplasms, Experimental -- chemistry
- Phenotype
- Phosphorylation
- Point Mutation
- Protein-Tyrosine Kinases -- genetics
- Proto-Oncogene Proteins
- STAT5 Transcription Factor
- Signal Transduction -- physiology
- Suppression, Genetic
- Trans-Activators -- metabolism
- Transcription Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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