Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways.
Luo, H
Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways. [electronic resource] - Molecular and cellular biology Mar 1997 - 1562-71 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0270-7306
10.1128/MCB.17.3.1562 doi
Amino Acid Sequence
Animals
COS Cells
DNA--metabolism
DNA-Binding Proteins--metabolism
Drosophila Proteins
Drosophila melanogaster--genetics
Female
Glutamic Acid--genetics
Janus Kinase 2
Janus Kinases
Leukemia, Experimental--genetics
Male
Melanins--analysis
Mice
Milk Proteins
Molecular Sequence Data
Neoplasms, Experimental--chemistry
Phenotype
Phosphorylation
Point Mutation
Protein-Tyrosine Kinases--genetics
Proto-Oncogene Proteins
STAT5 Transcription Factor
Signal Transduction--physiology
Suppression, Genetic
Trans-Activators--metabolism
Transcription Factors
Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways. [electronic resource] - Molecular and cellular biology Mar 1997 - 1562-71 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0270-7306
10.1128/MCB.17.3.1562 doi
Amino Acid Sequence
Animals
COS Cells
DNA--metabolism
DNA-Binding Proteins--metabolism
Drosophila Proteins
Drosophila melanogaster--genetics
Female
Glutamic Acid--genetics
Janus Kinase 2
Janus Kinases
Leukemia, Experimental--genetics
Male
Melanins--analysis
Mice
Milk Proteins
Molecular Sequence Data
Neoplasms, Experimental--chemistry
Phenotype
Phosphorylation
Point Mutation
Protein-Tyrosine Kinases--genetics
Proto-Oncogene Proteins
STAT5 Transcription Factor
Signal Transduction--physiology
Suppression, Genetic
Trans-Activators--metabolism
Transcription Factors