Hepatic microsomal enzyme induction, beta-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil, or bezafibrate in the CD rat. [electronic resource]
Producer: 19970224Description: 143-50 p. digitalISSN:- 0041-008X
- Animals
- Anticholesteremic Agents -- pharmacology
- Bezafibrate -- pharmacology
- Clofibrate -- pharmacology
- Cyclin-Dependent Kinases -- biosynthesis
- Cytochrome P-450 CYP1A1 -- biosynthesis
- Cytochrome P-450 CYP4A
- Cytochrome P-450 Enzyme System -- biosynthesis
- Dose-Response Relationship, Drug
- Enzyme Induction -- drug effects
- Female
- Gemfibrozil -- pharmacology
- Isoenzymes -- biosynthesis
- Liver -- drug effects
- Male
- Microbodies -- drug effects
- Microsomes, Liver -- drug effects
- Mixed Function Oxygenases -- biosynthesis
- Organ Size -- drug effects
- Oxidation-Reduction
- Palmitoyl Coenzyme A -- metabolism
- Proliferating Cell Nuclear Antigen -- biosynthesis
- Rats
- Rats, Inbred Strains -- genetics
- Sex Characteristics
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Publication Type: Comparative Study; Journal Article
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