Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase. [electronic resource]
Producer: 19970218Description: 862-72 p. digitalISSN:- 0270-7306
- Alkyl and Aryl Transferases
- Animals
- Axons
- Biomarkers -- analysis
- Blood
- Cell Division
- Cells, Cultured
- Colforsin -- pharmacology
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Glia Maturation Factor
- Hyperplasia
- Mice
- Mice, Mutant Strains
- Mutation
- Myelin P0 Protein -- analysis
- Neoplasm Invasiveness
- Neovascularization, Pathologic -- physiopathology
- Nerve Growth Factors -- pharmacology
- Nerve Tissue Proteins -- pharmacology
- Neurofibromatosis 1 -- pathology
- Neurofibromin 1
- Oligopeptides -- pharmacology
- Phenotype
- Protein Prenylation
- Proteins -- physiology
- Schwann Cells -- pathology
- Transferases -- antagonists & inhibitors
No physical items for this record
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
There are no comments on this title.
Log in to your account to post a comment.