Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment. [electronic resource]
Producer: 19970317Description: 1249-56 p. digitalISSN:- 0893-228X
- Animals
- Biotransformation
- Chlorobenzenes -- pharmacokinetics
- Chromatography, High Pressure Liquid
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- metabolism
- Humans
- In Vitro Techniques
- Insecticides -- pharmacokinetics
- Isoenzymes -- antagonists & inhibitors
- Male
- Microsomes, Liver -- drug effects
- Protein Binding
- Rats
- Rats, Inbred F344
- Rats, Sprague-Dawley
- Rats, Wistar
- Risk Assessment
- Species Specificity
- Spectrophotometry, Ultraviolet
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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