Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts. [electronic resource]
Producer: 19970107Description: 1991-9 p. digitalISSN:- 0950-9232
- Actins -- drug effects
- Alkyl and Aryl Transferases
- Animals
- Benzamides -- pharmacology
- Cell Cycle -- drug effects
- Cell Division -- drug effects
- Cell Transformation, Neoplastic -- genetics
- Cells, Cultured
- Cytoskeleton -- drug effects
- DNA -- biosynthesis
- Diterpenes -- metabolism
- Enzyme Inhibitors -- pharmacology
- Farnesol -- metabolism
- Fibroblasts -- cytology
- G1 Phase -- drug effects
- GTP-Binding Proteins -- drug effects
- Genes, ras
- Lovastatin -- pharmacology
- Methionine -- analogs & derivatives
- Mevalonic Acid -- pharmacology
- Mice
- Protein Prenylation -- drug effects
- Protein Serine-Threonine Kinases -- genetics
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-raf
- Resting Phase, Cell Cycle -- drug effects
- S Phase -- drug effects
- Transferases -- antagonists & inhibitors
- rap GTP-Binding Proteins
- ras Proteins -- drug effects
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
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