Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in jurkat T cells. Evidence for the importance of Ras in a pathway that is controlled by dual receptor stimulation. [electronic resource]
Producer: 19961226Description: 27366-73 p. digitalISSN:- 0021-9258
- Base Sequence
- CD28 Antigens -- physiology
- Calcium-Calmodulin-Dependent Protein Kinases -- metabolism
- DNA Primers
- Enzyme Activation
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Neoplastic
- Humans
- Interleukin-2 -- biosynthesis
- JNK Mitogen-Activated Protein Kinases
- Jurkat Cells
- Kinetics
- MAP Kinase Kinase 1
- MAP Kinase Kinase Kinases
- Mitogen-Activated Protein Kinase Kinases
- Mitogen-Activated Protein Kinases
- Polymerase Chain Reaction
- Promoter Regions, Genetic
- Protein Serine-Threonine Kinases -- metabolism
- Protein-Tyrosine Kinases -- metabolism
- RNA, Messenger -- biosynthesis
- Receptor-CD3 Complex, Antigen, T-Cell -- physiology
- T-Lymphocytes
- Transcription, Genetic
- Transcriptional Activation
- ras Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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