Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in jurkat T cells. Evidence for the importance of Ras in a pathway that is controlled by dual receptor stimulation.

Faris, M

Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in jurkat T cells. Evidence for the importance of Ras in a pathway that is controlled by dual receptor stimulation. [electronic resource] - The Journal of biological chemistry Nov 1996 - 27366-73 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.271.44.27366 doi


Base Sequence
CD28 Antigens--physiology
Calcium-Calmodulin-Dependent Protein Kinases--metabolism
DNA Primers
Enzyme Activation
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Neoplastic
Humans
Interleukin-2--biosynthesis
JNK Mitogen-Activated Protein Kinases
Jurkat Cells
Kinetics
MAP Kinase Kinase 1
MAP Kinase Kinase Kinases
Mitogen-Activated Protein Kinase Kinases
Mitogen-Activated Protein Kinases
Polymerase Chain Reaction
Promoter Regions, Genetic
Protein Serine-Threonine Kinases--metabolism
Protein-Tyrosine Kinases--metabolism
RNA, Messenger--biosynthesis
Receptor-CD3 Complex, Antigen, T-Cell--physiology
T-Lymphocytes
Transcription, Genetic
Transcriptional Activation
ras Proteins--metabolism