The fumagillin analogue TNP-470 inhibits DNA synthesis of vascular smooth muscle cells stimulated by platelet-derived growth factor and insulin-like growth factor-I. Possible involvement of cyclin-dependent kinase 2. [electronic resource]
Producer: 19961127Description: 757-64 p. digitalISSN:- 0009-7330
- Animals
- Antibiotics, Antineoplastic -- pharmacology
- Becaplermin
- CDC2-CDC28 Kinases
- Cattle
- Cells, Cultured
- Cyclin-Dependent Kinase 2
- Cyclin-Dependent Kinases -- metabolism
- Cyclohexanes
- DNA Replication -- drug effects
- Drug Antagonism
- Insulin-Like Growth Factor I -- pharmacology
- Muscle, Smooth, Vascular -- metabolism
- O-(Chloroacetylcarbamoyl)fumagillol
- Platelet-Derived Growth Factor -- pharmacology
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins c-sis
- Sesquiterpenes -- pharmacology
- Signal Transduction -- drug effects
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.