Chronic exposure of LLC-PK1 epithelia to the phorbol ester TPA produces polyp-like foci with leaky tight junctions and altered protein kinase C-alpha expression and localization. [electronic resource]
Producer: 19961024Description: 12-22 p. digitalISSN:- 0014-4827
- Animals
- Carcinoma
- Cell Membrane -- enzymology
- Cell Membrane Permeability -- drug effects
- Cell Transformation, Neoplastic -- pathology
- Clone Cells
- Coloring Agents
- Cytosol -- enzymology
- Electric Impedance
- Epithelial Cells
- Epithelium -- enzymology
- Isoenzymes -- analysis
- LLC-PK1 Cells -- drug effects
- Mannitol -- metabolism
- Protein Kinase C -- analysis
- Protein Kinase C-alpha
- Ruthenium Red
- Swine
- Tetradecanoylphorbol Acetate -- pharmacology
- Tight Junctions -- drug effects
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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