Targeted replacement of the mycocerosic acid synthase gene in Mycobacterium bovis BCG produces a mutant that lacks mycosides. [electronic resource]
Producer: 19960718Description: 4787-92 p. digitalISSN:- 0027-8424
- Acyltransferases -- genetics
- Anti-Bacterial Agents -- pharmacology
- Base Sequence
- Cinnamates
- DNA Primers -- genetics
- DNA, Bacterial -- genetics
- Drug Resistance, Microbial -- genetics
- Escherichia coli -- genetics
- Fatty Acids -- biosynthesis
- Gene Targeting
- Genes, Bacterial
- Hygromycin B -- analogs & derivatives
- Molecular Sequence Data
- Mutation
- Mycobacterium bovis -- drug effects
- Polymerase Chain Reaction
- Transformation, Genetic
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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