Targeted replacement of the mycocerosic acid synthase gene in Mycobacterium bovis BCG produces a mutant that lacks mycosides.

Azad, A K

Targeted replacement of the mycocerosic acid synthase gene in Mycobacterium bovis BCG produces a mutant that lacks mycosides. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America May 1996 - 4787-92 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.93.10.4787 doi


Acyltransferases--genetics
Anti-Bacterial Agents--pharmacology
Base Sequence
Cinnamates
DNA Primers--genetics
DNA, Bacterial--genetics
Drug Resistance, Microbial--genetics
Escherichia coli--genetics
Fatty Acids--biosynthesis
Gene Targeting
Genes, Bacterial
Hygromycin B--analogs & derivatives
Molecular Sequence Data
Mutation
Mycobacterium bovis--drug effects
Polymerase Chain Reaction
Transformation, Genetic