The human homologue of rat NG2, a chondroitin sulfate proteoglycan, is not expressed on the cell surface of normal hematopoietic cells but is expressed by acute myeloid leukemia blasts from poor-prognosis patients with abnormalities of chromosome band 11q23. [electronic resource]
Producer: 19960301Description: 1123-33 p. digitalISSN:- 0006-4971
- Actuarial Analysis
- Acute Disease
- Adolescent
- Amino Acid Sequence
- Aneuploidy
- Animals
- Antibodies, Monoclonal -- immunology
- Antigens -- biosynthesis
- Antigens, Neoplasm -- biosynthesis
- Biomarkers, Tumor -- analysis
- Bone Marrow -- pathology
- Cell Line, Transformed
- Child
- Child, Preschool
- Chromosome Aberrations
- Chromosomes, Human, Pair 11 -- ultrastructure
- DNA-Binding Proteins -- genetics
- Female
- HeLa Cells -- chemistry
- Hematopoietic Stem Cells -- metabolism
- Histone-Lysine N-Methyltransferase
- Humans
- Leukemia, Monocytic, Acute -- genetics
- Leukemia, Myeloid -- genetics
- Leukemia, Myelomonocytic, Acute -- genetics
- Male
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Myeloid-Lymphoid Leukemia Protein
- Neoplastic Stem Cells -- metabolism
- Prognosis
- Proteoglycans -- biosynthesis
- Proto-Oncogenes
- Rats
- Survival Rate
- Transcription Factors
- Treatment Outcome
- Tumor Cells, Cultured
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Publication Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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