The human homologue of rat NG2, a chondroitin sulfate proteoglycan, is not expressed on the cell surface of normal hematopoietic cells but is expressed by acute myeloid leukemia blasts from poor-prognosis patients with abnormalities of chromosome band 11q23.
Smith, F O
The human homologue of rat NG2, a chondroitin sulfate proteoglycan, is not expressed on the cell surface of normal hematopoietic cells but is expressed by acute myeloid leukemia blasts from poor-prognosis patients with abnormalities of chromosome band 11q23. [electronic resource] - Blood Feb 1996 - 1123-33 p. digital
Publication Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0006-4971
Actuarial Analysis
Acute Disease
Adolescent
Amino Acid Sequence
Aneuploidy
Animals
Antibodies, Monoclonal--immunology
Antigens--biosynthesis
Antigens, Neoplasm--biosynthesis
Biomarkers, Tumor--analysis
Bone Marrow--pathology
Cell Line, Transformed
Child
Child, Preschool
Chromosome Aberrations
Chromosomes, Human, Pair 11--ultrastructure
DNA-Binding Proteins--genetics
Female
HeLa Cells--chemistry
Hematopoietic Stem Cells--metabolism
Histone-Lysine N-Methyltransferase
Humans
Leukemia, Monocytic, Acute--genetics
Leukemia, Myeloid--genetics
Leukemia, Myelomonocytic, Acute--genetics
Male
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Myeloid-Lymphoid Leukemia Protein
Neoplastic Stem Cells--metabolism
Prognosis
Proteoglycans--biosynthesis
Proto-Oncogenes
Rats
Survival Rate
Transcription Factors
Treatment Outcome
Tumor Cells, Cultured
The human homologue of rat NG2, a chondroitin sulfate proteoglycan, is not expressed on the cell surface of normal hematopoietic cells but is expressed by acute myeloid leukemia blasts from poor-prognosis patients with abnormalities of chromosome band 11q23. [electronic resource] - Blood Feb 1996 - 1123-33 p. digital
Publication Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0006-4971
Actuarial Analysis
Acute Disease
Adolescent
Amino Acid Sequence
Aneuploidy
Animals
Antibodies, Monoclonal--immunology
Antigens--biosynthesis
Antigens, Neoplasm--biosynthesis
Biomarkers, Tumor--analysis
Bone Marrow--pathology
Cell Line, Transformed
Child
Child, Preschool
Chromosome Aberrations
Chromosomes, Human, Pair 11--ultrastructure
DNA-Binding Proteins--genetics
Female
HeLa Cells--chemistry
Hematopoietic Stem Cells--metabolism
Histone-Lysine N-Methyltransferase
Humans
Leukemia, Monocytic, Acute--genetics
Leukemia, Myeloid--genetics
Leukemia, Myelomonocytic, Acute--genetics
Male
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Myeloid-Lymphoid Leukemia Protein
Neoplastic Stem Cells--metabolism
Prognosis
Proteoglycans--biosynthesis
Proto-Oncogenes
Rats
Survival Rate
Transcription Factors
Treatment Outcome
Tumor Cells, Cultured