Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes. [electronic resource]
Producer: 19930923Description: 7593-7 p. digitalISSN:- 0027-8424
- Animals
- Antibodies, Monoclonal
- Base Sequence
- Chromosomes, Fungal
- Gene Expression Regulation
- Genes, Synthetic
- Globins -- biosynthesis
- Hemoglobin A -- genetics
- Humans
- Liver -- metabolism
- Mice
- Mice, Transgenic
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Organ Specificity
- Polymerase Chain Reaction -- methods
- Saccharomyces cerevisiae -- genetics
- Yolk Sac -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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