Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes.
Peterson, K R
Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Aug 1993 - 7593-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.90.16.7593 doi
Animals
Antibodies, Monoclonal
Base Sequence
Chromosomes, Fungal
Gene Expression Regulation
Genes, Synthetic
Globins--biosynthesis
Hemoglobin A--genetics
Humans
Liver--metabolism
Mice
Mice, Transgenic
Molecular Sequence Data
Oligodeoxyribonucleotides
Organ Specificity
Polymerase Chain Reaction--methods
Saccharomyces cerevisiae--genetics
Yolk Sac--metabolism
Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Aug 1993 - 7593-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.90.16.7593 doi
Animals
Antibodies, Monoclonal
Base Sequence
Chromosomes, Fungal
Gene Expression Regulation
Genes, Synthetic
Globins--biosynthesis
Hemoglobin A--genetics
Humans
Liver--metabolism
Mice
Mice, Transgenic
Molecular Sequence Data
Oligodeoxyribonucleotides
Organ Specificity
Polymerase Chain Reaction--methods
Saccharomyces cerevisiae--genetics
Yolk Sac--metabolism