Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants. [electronic resource]
Producer: 19931201Description: 22322-30 p. digitalISSN:- 0021-9258
- Amino Acid Sequence
- Base Sequence
- Camptothecin -- toxicity
- Chromatography
- Chromatography, Affinity
- Chromatography, Ion Exchange
- DNA Topoisomerases, Type I -- genetics
- Drug Resistance, Microbial -- genetics
- Durapatite
- Humans
- Molecular Sequence Data
- Molecular Weight
- Mutagenesis, Site-Directed
- Oligodeoxyribonucleotides
- Plasmids
- Point Mutation
- Restriction Mapping
- Saccharomyces cerevisiae -- drug effects
- Sequence Homology, Amino Acid
- Substrate Specificity
- Tyrosine
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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