Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants.

Knab, A M

Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants. [electronic resource] - The Journal of biological chemistry Oct 1993 - 22322-30 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258


Amino Acid Sequence
Base Sequence
Camptothecin--toxicity
Chromatography
Chromatography, Affinity
Chromatography, Ion Exchange
DNA Topoisomerases, Type I--genetics
Drug Resistance, Microbial--genetics
Durapatite
Humans
Molecular Sequence Data
Molecular Weight
Mutagenesis, Site-Directed
Oligodeoxyribonucleotides
Plasmids
Point Mutation
Restriction Mapping
Saccharomyces cerevisiae--drug effects
Sequence Homology, Amino Acid
Substrate Specificity
Tyrosine