Conjugation of glutathione and other thiols with bioreductively activated mitomycin C. Effect of thiols on the reductive activation rate. [electronic resource]
Producer: 19941004Description: 390-400 p. digitalISSN:- 0893-228X
- Acetylcysteine -- chemistry
- Animals
- Biotransformation
- Cell-Free System
- Chromatography, High Pressure Liquid
- Glutathione -- metabolism
- In Vitro Techniques
- Inactivation, Metabolic
- Magnetic Resonance Spectroscopy
- Male
- Mercaptoethanol -- chemistry
- Microsomes, Liver -- metabolism
- Mitomycin -- chemistry
- NADP -- metabolism
- Oxidation-Reduction
- Rats
- Rats, Sprague-Dawley
- Spectrophotometry, Ultraviolet
- Sulfhydryl Compounds -- metabolism
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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