Conjugation of glutathione and other thiols with bioreductively activated mitomycin C. Effect of thiols on the reductive activation rate.

Sharma, M

Conjugation of glutathione and other thiols with bioreductively activated mitomycin C. Effect of thiols on the reductive activation rate. [electronic resource] - Chemical research in toxicology - 390-400 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0893-228X

10.1021/tx00039a017 doi


Acetylcysteine--chemistry
Animals
Biotransformation
Cell-Free System
Chromatography, High Pressure Liquid
Glutathione--metabolism
In Vitro Techniques
Inactivation, Metabolic
Magnetic Resonance Spectroscopy
Male
Mercaptoethanol--chemistry
Microsomes, Liver--metabolism
Mitomycin--chemistry
NADP--metabolism
Oxidation-Reduction
Rats
Rats, Sprague-Dawley
Spectrophotometry, Ultraviolet
Sulfhydryl Compounds--metabolism