IgG immune complexes inhibit IFN-gamma-induced transcription of the Fc gamma RI gene in human monocytes by preventing the tyrosine phosphorylation of the p91 (Stat1) transcription factor. [electronic resource]
Producer: 19950119Description: 318-25 p. digitalISSN:- 0022-1767
- Antigen-Antibody Complex -- immunology
- Base Sequence
- DNA-Binding Proteins -- metabolism
- Down-Regulation
- Gene Expression Regulation
- Humans
- Immunoglobulin G -- immunology
- Interferon-gamma -- antagonists & inhibitors
- Janus Kinase 1
- Janus Kinase 2
- Molecular Sequence Data
- Monocytes -- metabolism
- Phosphorylation -- drug effects
- Protein Processing, Post-Translational
- Protein-Tyrosine Kinases -- metabolism
- Proto-Oncogene Proteins
- Receptors, IgG -- biosynthesis
- Recombinant Proteins
- STAT1 Transcription Factor
- Trans-Activators -- metabolism
- Transcription, Genetic
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Publication Type: Journal Article
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