IgG immune complexes inhibit IFN-gamma-induced transcription of the Fc gamma RI gene in human monocytes by preventing the tyrosine phosphorylation of the p91 (Stat1) transcription factor.

Feldman, G M

IgG immune complexes inhibit IFN-gamma-induced transcription of the Fc gamma RI gene in human monocytes by preventing the tyrosine phosphorylation of the p91 (Stat1) transcription factor. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Jan 1995 - 318-25 p. digital

Publication Type: Journal Article

0022-1767


Antigen-Antibody Complex--immunology
Base Sequence
DNA-Binding Proteins--metabolism
Down-Regulation
Gene Expression Regulation
Humans
Immunoglobulin G--immunology
Interferon-gamma--antagonists & inhibitors
Janus Kinase 1
Janus Kinase 2
Molecular Sequence Data
Monocytes--metabolism
Phosphorylation--drug effects
Protein Processing, Post-Translational
Protein-Tyrosine Kinases--metabolism
Proto-Oncogene Proteins
Receptors, IgG--biosynthesis
Recombinant Proteins
STAT1 Transcription Factor
Trans-Activators--metabolism
Transcription, Genetic