Metabolism of taxol by human and rat liver in vitro: a screen for drug interactions and interspecies differences. [electronic resource]
Producer: 19950630Description: 107-14 p. digitalISSN:- 0344-5704
- Animals
- Biotransformation
- Cimetidine -- pharmacology
- Cytochrome P-450 Enzyme System -- metabolism
- Dexamethasone -- pharmacology
- Diphenhydramine -- pharmacology
- Drug Evaluation, Preclinical -- methods
- Drug Interactions
- Glycerol -- analogs & derivatives
- Humans
- In Vitro Techniques
- Ketoconazole -- pharmacology
- Kinetics
- Liver -- drug effects
- Microsomes, Liver -- drug effects
- Paclitaxel -- analogs & derivatives
- Quinidine -- pharmacology
- Rats
- Species Specificity
- Surface-Active Agents -- pharmacology
- Taxoids
- Tritium
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Publication Type: Comparative Study; Journal Article
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