Metabolism of taxol by human and rat liver in vitro: a screen for drug interactions and interspecies differences.

Jamis-Dow, C A

Metabolism of taxol by human and rat liver in vitro: a screen for drug interactions and interspecies differences. [electronic resource] - Cancer chemotherapy and pharmacology 1995 - 107-14 p. digital

Publication Type: Comparative Study; Journal Article

0344-5704

10.1007/BF00689193 doi


Animals
Biotransformation
Cimetidine--pharmacology
Cytochrome P-450 Enzyme System--metabolism
Dexamethasone--pharmacology
Diphenhydramine--pharmacology
Drug Evaluation, Preclinical--methods
Drug Interactions
Glycerol--analogs & derivatives
Humans
In Vitro Techniques
Ketoconazole--pharmacology
Kinetics
Liver--drug effects
Microsomes, Liver--drug effects
Paclitaxel--analogs & derivatives
Quinidine--pharmacology
Rats
Species Specificity
Surface-Active Agents--pharmacology
Taxoids
Tritium