Early CD34high cells can be separated into KIThigh cells in which transforming growth factor-beta (TGF-beta) downmodulates c-kit and KITlow cells in which anti-TGF-beta upmodulates c-kit. [electronic resource]
Producer: 19951003Description: 1729-35 p. digitalISSN:- 0006-4971
- Antibodies, Monoclonal -- pharmacology
- Antigens, CD -- analysis
- Antigens, CD34
- Biomarkers, Tumor -- analysis
- Cell Separation -- methods
- Erythropoietin -- pharmacology
- Fetal Blood -- cytology
- Gene Expression
- Glyceraldehyde-3-Phosphate Dehydrogenases -- biosynthesis
- Granulocyte Colony-Stimulating Factor -- pharmacology
- Hematopoietic Cell Growth Factors -- pharmacology
- Hematopoietic Stem Cells -- cytology
- Humans
- Infant, Newborn
- Interleukin-3 -- pharmacology
- Interleukin-6 -- pharmacology
- Kinetics
- Proto-Oncogene Proteins -- analysis
- Proto-Oncogene Proteins c-kit
- Proto-Oncogenes
- RNA, Messenger -- analysis
- Receptor Protein-Tyrosine Kinases -- analysis
- Receptor, Macrophage Colony-Stimulating Factor -- biosynthesis
- Receptors, Colony-Stimulating Factor -- analysis
- Receptors, Transferrin -- biosynthesis
- Recombinant Proteins -- pharmacology
- Transforming Growth Factor beta -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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