Effect of modification of one histidine residue on the enzymatic and pharmacological properties of a toxic phospholipase A2 from Naja nigricollis snake venom and less toxic phospholipases A2 from Hemachatus haemachatus and Naja atra snake venoms. [electronic resource]
Producer: 19810623Description: 61-71 p. digitalISSN:- 0041-0101
- Animals
- Chemical Phenomena
- Chemistry
- Elapid Venoms -- analysis
- Erythrocytes -- drug effects
- Guinea Pigs
- Histidine
- Hydrolysis
- In Vitro Techniques
- Lethal Dose 50
- Male
- Mice
- Phospholipases -- pharmacology
- Phospholipases A -- metabolism
- Phospholipases A2
- Phospholipids
- Rats
- Snake Venoms -- analysis
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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