Effect of modification of one histidine residue on the enzymatic and pharmacological properties of a toxic phospholipase A2 from Naja nigricollis snake venom and less toxic phospholipases A2 from Hemachatus haemachatus and Naja atra snake venoms.

Condrea, E

Effect of modification of one histidine residue on the enzymatic and pharmacological properties of a toxic phospholipase A2 from Naja nigricollis snake venom and less toxic phospholipases A2 from Hemachatus haemachatus and Naja atra snake venoms. [electronic resource] - Toxicon : official journal of the International Society on Toxinology 1981 - 61-71 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0041-0101

10.1016/0041-0101(81)90118-5 doi


Animals
Chemical Phenomena
Chemistry
Elapid Venoms--analysis
Erythrocytes--drug effects
Guinea Pigs
Histidine
Hydrolysis
In Vitro Techniques
Lethal Dose 50
Male
Mice
Phospholipases--pharmacology
Phospholipases A--metabolism
Phospholipases A2
Phospholipids
Rats
Snake Venoms--analysis
Structure-Activity Relationship