Amplification of the UMP synthase gene and enzyme overproduction in pyrazofurin-resistant rat hepatoma cells. Molecular cloning of a cDNA for UMP synthase. [electronic resource]
Producer: 19840316Description: 1848-53 p. digitalISSN:- 0021-9258
- Amides
- Animals
- Antibiotics, Antineoplastic -- toxicity
- Base Sequence
- Carboxy-Lyases -- genetics
- Cell Line
- Cloning, Molecular
- DNA -- metabolism
- Drug Resistance
- Gene Amplification
- Genes
- Liver Neoplasms, Experimental -- enzymology
- Multienzyme Complexes -- genetics
- Orotate Phosphoribosyltransferase -- genetics
- Orotidine-5'-Phosphate Decarboxylase -- genetics
- Pentosyltransferases -- genetics
- Plasmids
- Pyrazoles
- RNA, Messenger -- genetics
- Rats
- Ribonucleosides -- toxicity
- Ribose
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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