Methoxsalen decreases the metabolic activation and prevents the hepatotoxicity and nephrotoxicity of chloroform in mice. [electronic resource]
Producer: 19871211Description: 266-73 p. digitalISSN:- 0041-008X
- 7-Alkoxycoumarin O-Dealkylase
- Aminopyrine N-Demethylase -- metabolism
- Animals
- Biotransformation
- Chloroform -- metabolism
- Cytochrome P-450 Enzyme System -- metabolism
- Dose-Response Relationship, Drug
- Kidney -- drug effects
- Liver -- drug effects
- Male
- Methoxsalen -- pharmacology
- Mice
- Mice, Inbred Strains
- Microsomes -- enzymology
- Microsomes, Liver -- enzymology
- NADPH-Ferrihemoprotein Reductase -- metabolism
- Oxygenases -- metabolism
- Proteins -- metabolism
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Publication Type: Journal Article
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