SIRT3 deficiency is resistant to autophagy-dependent ferroptosis by inhibiting the AMPK/mTOR pathway and promoting GPX4 levels. [electronic resource]
Producer: 20210316Description: 8839-8851 p. digitalISSN:- 1097-4652
- AMP-Activated Protein Kinases -- metabolism
- Autophagy -- physiology
- Ferroptosis -- physiology
- Glutathione Peroxidase -- metabolism
- Humans
- Lipid Peroxidation -- drug effects
- Phospholipid Hydroperoxide Glutathione Peroxidase -- metabolism
- Reactive Oxygen Species -- metabolism
- Sirtuin 3 -- deficiency
- TOR Serine-Threonine Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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