The genomic landscape of undifferentiated embryonal sarcoma of the liver is typified by C19MC structural rearrangement and overexpression combined with TP53 mutation or loss. [electronic resource]
Producer: 20200720Description: e1008642 p. digitalISSN:- 1553-7404
- Aneuploidy
- Child
- Child, Preschool
- Chromosome Breakpoints
- Chromosomes, Human, Pair 19 -- genetics
- Female
- Gene Expression Regulation, Neoplastic
- Genes, ras -- genetics
- Genomic Instability -- genetics
- Humans
- Infant
- Liver Neoplasms -- genetics
- Male
- MicroRNAs -- genetics
- Mutation
- Neoplasms, Germ Cell and Embryonal -- genetics
- Sarcoma -- genetics
- Transcription Initiation Site
- Tumor Suppressor Protein p53 -- deficiency
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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