The genomic landscape of undifferentiated embryonal sarcoma of the liver is typified by C19MC structural rearrangement and overexpression combined with TP53 mutation or loss.

Setty, Bhuvana A

The genomic landscape of undifferentiated embryonal sarcoma of the liver is typified by C19MC structural rearrangement and overexpression combined with TP53 mutation or loss. [electronic resource] - PLoS genetics 04 2020 - e1008642 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1553-7404

10.1371/journal.pgen.1008642 doi


Aneuploidy
Child
Child, Preschool
Chromosome Breakpoints
Chromosomes, Human, Pair 19--genetics
Female
Gene Expression Regulation, Neoplastic
Genes, ras--genetics
Genomic Instability--genetics
Humans
Infant
Liver Neoplasms--genetics
Male
MicroRNAs--genetics
Mutation
Neoplasms, Germ Cell and Embryonal--genetics
Sarcoma--genetics
Transcription Initiation Site
Tumor Suppressor Protein p53--deficiency
Up-Regulation