Co-targeting bromodomain and extra-terminal proteins and MCL1 induces synergistic cell death in melanoma. [electronic resource]
Producer: 20210412Description: 2176-2189 p. digitalISSN:- 1097-0215
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- metabolism
- Cell Death -- drug effects
- Cell Line, Tumor
- Down-Regulation -- drug effects
- Drug Resistance, Neoplasm -- drug effects
- Drug Synergism
- Humans
- Male
- Melanoma -- drug therapy
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Myeloid Cell Leukemia Sequence 1 Protein -- metabolism
- Proteins -- metabolism
- Pyrimidines -- pharmacology
- Thiophenes -- pharmacology
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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