A randomized proof-of-mechanism trial applying the 'fast-fail' approach to evaluating κ-opioid antagonism as a treatment for anhedonia. [electronic resource]
Producer: 20200824Description: 760-768 p. digitalISSN:- 1546-170X
- Adult
- Anhedonia -- drug effects
- Anxiety Disorders -- complications
- Benzamides -- therapeutic use
- Central Nervous System Agents -- therapeutic use
- Double-Blind Method
- Female
- Humans
- Male
- Middle Aged
- Mood Disorders -- complications
- Narcotic Antagonists -- therapeutic use
- Proof of Concept Study
- Pyrrolidines -- therapeutic use
- Receptors, Opioid, kappa -- antagonists & inhibitors
- Time Factors
- Treatment Outcome
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Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural
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