A randomized proof-of-mechanism trial applying the 'fast-fail' approach to evaluating κ-opioid antagonism as a treatment for anhedonia. (Record no. 30799075)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02130 a2200625 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250518093601.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 202008s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1546-170X |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1038/s41591-020-0806-7 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Krystal, Andrew D |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20200824 |
| 245 00 - TITLE STATEMENT | |
| Title | A randomized proof-of-mechanism trial applying the 'fast-fail' approach to evaluating κ-opioid antagonism as a treatment for anhedonia. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Nature medicine |
| Date of publication, distribution, etc. | 05 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 760-768 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adult |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Anhedonia |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Anxiety Disorders |
| General subdivision | complications |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Benzamides |
| General subdivision | therapeutic use |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Central Nervous System Agents |
| General subdivision | therapeutic use |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Double-Blind Method |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Middle Aged |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mood Disorders |
| General subdivision | complications |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Narcotic Antagonists |
| General subdivision | therapeutic use |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proof of Concept Study |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrrolidines |
| General subdivision | therapeutic use |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptors, Opioid, kappa |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Time Factors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Treatment Outcome |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pizzagalli, Diego A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Smoski, Moria |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mathew, Sanjay J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nurnberger, John |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lisanby, Sarah H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iosifescu, Dan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Murrough, James W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yang, Hongqiu |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Weiner, Richard D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Calabrese, Joseph R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sanacora, Gerard |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hermes, Gretchen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Keefe, Richard S E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Song, Allen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Goodman, Wayne |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Szabo, Steven T |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Whitton, Alexis E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gao, Keming |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Potter, William Z |
| 773 0# - HOST ITEM ENTRY | |
| Title | Nature medicine |
| Related parts | vol. 26 |
| -- | no. 5 |
| -- | p. 760-768 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1038/s41591-020-0806-7">https://doi.org/10.1038/s41591-020-0806-7</a> |
| Public note | Available from publisher's website |
No items available.