A physiological model of granulopoiesis to predict clinical drug induced neutropenia from in vitro bone marrow studies: with application to a cell cycle inhibitor. [electronic resource]
Producer: 20210430Description: 163-182 p. digitalISSN:- 1573-8744
- Algorithms
- Antineoplastic Agents -- pharmacology
- Bone Marrow -- drug effects
- Cell Cycle -- drug effects
- Cell Movement
- Filgrastim -- pharmacology
- Granulocyte Colony-Stimulating Factor -- pharmacology
- Granulocytes -- drug effects
- Hematopoiesis -- drug effects
- Humans
- Leukocyte Count
- Models, Biological
- Neutropenia -- chemically induced
- Neutrophils -- drug effects
- Piperazines -- pharmacology
- Polyethylene Glycols -- pharmacology
- Pyridines -- pharmacology
- Stem Cells -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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