Reduction of inflammation in a chronic periodontitis model in rats by TNF-α gene silencing with a topically applied siRNA-loaded calcium phosphate paste. [electronic resource]
Producer: 20210128Description: 263-279 p. digitalISSN:- 1878-7568
- Alkaline Phosphatase -- metabolism
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Calcium Phosphates -- chemistry
- Cell Line
- Cell Survival -- drug effects
- Chronic Periodontitis -- diagnostic imaging
- Disease Models, Animal
- Gene Silencing
- Gingiva -- pathology
- Inflammation -- pathology
- Male
- Mice, Inbred C57BL
- Monocytes -- cytology
- Nanoparticles -- chemistry
- Particle Size
- RNA, Small Interfering -- metabolism
- Rats, Wistar
- Tartrate-Resistant Acid Phosphatase -- metabolism
- Tumor Necrosis Factor-alpha -- genetics
- Wound Healing -- drug effects
- X-Ray Microtomography
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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