Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome. [electronic resource]
Producer: 20210211ISSN:- 2073-4409
- Animals
- Arthritis, Gouty -- complications
- Autophagy -- drug effects
- CARD Signaling Adaptor Proteins -- metabolism
- Cell Line
- Disease Models, Animal
- Humans
- Inflammasomes -- metabolism
- Inflammation -- complications
- Lipopolysaccharides
- Lysosomes -- drug effects
- Macrophages -- drug effects
- Male
- Mice, Inbred C57BL
- Mitochondria -- drug effects
- Models, Biological
- NLR Family, Pyrin Domain-Containing 3 Protein -- metabolism
- Organelle Biogenesis
- Protein Multimerization -- drug effects
- Pyrroles -- chemistry
- Sirtuin 1 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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