Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome.
Hsieh, Chih-Yu
Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome. [electronic resource] - Cells 01 2020
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2073-4409
10.3390/cells9020279 doi
Animals
Arthritis, Gouty--complications
Autophagy--drug effects
CARD Signaling Adaptor Proteins--metabolism
Cell Line
Disease Models, Animal
Humans
Inflammasomes--metabolism
Inflammation--complications
Lipopolysaccharides
Lysosomes--drug effects
Macrophages--drug effects
Male
Mice, Inbred C57BL
Mitochondria--drug effects
Models, Biological
NLR Family, Pyrin Domain-Containing 3 Protein--metabolism
Organelle Biogenesis
Protein Multimerization--drug effects
Pyrroles--chemistry
Sirtuin 1--metabolism
Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome. [electronic resource] - Cells 01 2020
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2073-4409
10.3390/cells9020279 doi
Animals
Arthritis, Gouty--complications
Autophagy--drug effects
CARD Signaling Adaptor Proteins--metabolism
Cell Line
Disease Models, Animal
Humans
Inflammasomes--metabolism
Inflammation--complications
Lipopolysaccharides
Lysosomes--drug effects
Macrophages--drug effects
Male
Mice, Inbred C57BL
Mitochondria--drug effects
Models, Biological
NLR Family, Pyrin Domain-Containing 3 Protein--metabolism
Organelle Biogenesis
Protein Multimerization--drug effects
Pyrroles--chemistry
Sirtuin 1--metabolism