Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents. [electronic resource]
Producer: 20200312Description: 111913 p. digitalISSN:- 1768-3254
- Aging -- drug effects
- Alzheimer Disease -- drug therapy
- Amyloid beta-Peptides -- antagonists & inhibitors
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- chemical synthesis
- Astrocytes -- drug effects
- Carbamates -- chemical synthesis
- Cell Line, Tumor
- Cell Survival -- drug effects
- Diosgenin -- chemical synthesis
- Dose-Response Relationship, Drug
- Drug Design
- Galactose -- administration & dosage
- Humans
- Inflammation -- drug therapy
- Male
- Mice
- Mice, Inbred ICR
- Molecular Structure
- Neuroprotective Agents -- chemical synthesis
- Oxidative Stress -- drug effects
- Protein Aggregates -- drug effects
- Structure-Activity Relationship
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Publication Type: Journal Article
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