A facile di-acid mono-amidation strategy to prepare cyclization-activating mono-carboxylate transporter 1-targeting gemcitabine prodrugs for enhanced oral delivery. [electronic resource]
Producer: 20201023Description: 118718 p. digitalISSN:- 1873-3476
- Administration, Oral
- Animals
- Antimetabolites, Antineoplastic -- administration & dosage
- Biological Availability
- Caco-2 Cells
- Cyclization
- Deoxycytidine -- administration & dosage
- Drug Delivery Systems
- Humans
- Hydrogen-Ion Concentration
- Intestinal Absorption
- Monocarboxylic Acid Transporters -- metabolism
- Prodrugs
- Rats
- Rats, Wistar
- Symporters -- metabolism
- Gemcitabine
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Publication Type: Comparative Study; Journal Article
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