Drug Screen Identifies Leflunomide for Treatment of Inflammatory Bowel Disease Caused by TTC7A Deficiency. [electronic resource]
Producer: 20200428Description: 1000-1015 p. digitalISSN:- 1528-0012
- Adaptor Proteins, Signal Transducing -- metabolism
- Animals
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- metabolism
- Colon -- cytology
- Enzyme Inhibitors -- pharmacology
- Gene Knockout Techniques
- Haploidy
- Humans
- Inflammatory Bowel Diseases -- drug therapy
- Leflunomide -- pharmacology
- Phosphorylation -- drug effects
- Proteins -- genetics
- X-Linked Inhibitor of Apoptosis Protein -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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