Inactivation of the AMPK-GATA3-ECHS1 Pathway Induces Fatty Acid Synthesis That Promotes Clear Cell Renal Cell Carcinoma Growth. [electronic resource]
Producer: 20200619Description: 319-333 p. digitalISSN:- 1538-7445
- AMP-Activated Protein Kinases -- metabolism
- Adult
- Aged
- Aged, 80 and over
- Amino Acids, Branched-Chain -- analysis
- Animals
- Carcinogenesis -- genetics
- Carcinoma, Renal Cell -- genetics
- Cell Line, Tumor
- Cell Movement -- genetics
- Cell Proliferation
- Down-Regulation
- Enoyl-CoA Hydratase -- metabolism
- Fatty Acids -- analysis
- Female
- GATA3 Transcription Factor -- metabolism
- Gene Expression Regulation, Neoplastic
- HEK293 Cells
- Humans
- Kidney -- pathology
- Kidney Neoplasms -- genetics
- Lipogenesis -- genetics
- Male
- Mechanistic Target of Rapamycin Complex 1 -- metabolism
- Mice, Knockout
- Middle Aged
- Nephrectomy
- Prognosis
- Progression-Free Survival
- Signal Transduction -- genetics
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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