Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors. [electronic resource]
Producer: 20201029Description: 15893 p. digitalISSN:- 2045-2322
- Adenosine Triphosphate -- metabolism
- Binding Sites
- Casein Kinase II -- antagonists & inhibitors
- Catalytic Domain
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Crystallography, X-Ray
- Holoenzymes -- chemistry
- Humans
- Kinetics
- Molecular Docking Simulation
- Peptides -- chemistry
- Phosphorylation
- Protein Kinase Inhibitors -- chemistry
- Protein Subunits -- antagonists & inhibitors
- Substrate Specificity
- Surface Plasmon Resonance
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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