Aflatoxin B1 enhances pyroptosis of hepatocytes and activation of Kupffer cells to promote liver inflammatory injury via dephosphorylation of cyclooxygenase-2: an in vitro, ex vivo and in vivo study. [electronic resource]
Producer: 20200827Description: 3305-3320 p. digitalISSN:- 1432-0738
- Aflatoxin B1 -- toxicity
- Animals
- Cell Line, Tumor
- Chemical and Drug Induced Liver Injury -- etiology
- Cyclooxygenase 2 -- metabolism
- HEK293 Cells
- Hepatocytes -- drug effects
- Humans
- Inflammation
- Interleukin-1beta -- metabolism
- Kupffer Cells -- drug effects
- Liver -- drug effects
- Mice, Inbred C57BL
- Phosphorylation
- Primary Cell Culture
- Pyroptosis -- drug effects
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Publication Type: Journal Article
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