Aflatoxin B1 enhances pyroptosis of hepatocytes and activation of Kupffer cells to promote liver inflammatory injury via dephosphorylation of cyclooxygenase-2: an in vitro, ex vivo and in vivo study.
Zhang, Li-Yin
Aflatoxin B1 enhances pyroptosis of hepatocytes and activation of Kupffer cells to promote liver inflammatory injury via dephosphorylation of cyclooxygenase-2: an in vitro, ex vivo and in vivo study. [electronic resource] - Archives of toxicology 11 2019 - 3305-3320 p. digital
Publication Type: Journal Article
1432-0738
10.1007/s00204-019-02572-w doi
Aflatoxin B1--toxicity
Animals
Cell Line, Tumor
Chemical and Drug Induced Liver Injury--etiology
Cyclooxygenase 2--metabolism
HEK293 Cells
Hepatocytes--drug effects
Humans
Inflammation
Interleukin-1beta--metabolism
Kupffer Cells--drug effects
Liver--drug effects
Mice, Inbred C57BL
Phosphorylation
Primary Cell Culture
Pyroptosis--drug effects
Aflatoxin B1 enhances pyroptosis of hepatocytes and activation of Kupffer cells to promote liver inflammatory injury via dephosphorylation of cyclooxygenase-2: an in vitro, ex vivo and in vivo study. [electronic resource] - Archives of toxicology 11 2019 - 3305-3320 p. digital
Publication Type: Journal Article
1432-0738
10.1007/s00204-019-02572-w doi
Aflatoxin B1--toxicity
Animals
Cell Line, Tumor
Chemical and Drug Induced Liver Injury--etiology
Cyclooxygenase 2--metabolism
HEK293 Cells
Hepatocytes--drug effects
Humans
Inflammation
Interleukin-1beta--metabolism
Kupffer Cells--drug effects
Liver--drug effects
Mice, Inbred C57BL
Phosphorylation
Primary Cell Culture
Pyroptosis--drug effects