dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice. [electronic resource]
Producer: 20201221Description: 235-253 p. digitalISSN:- 1525-0024
- Action Potentials
- Animals
- CRISPR-Associated Protein 9 -- genetics
- Cell Line, Tumor
- Disease Models, Animal
- Epilepsies, Myoclonic -- therapy
- Female
- GABAergic Neurons -- metabolism
- Genetic Therapy -- methods
- Hippocampus -- cytology
- Interneurons -- metabolism
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- NAV1.1 Voltage-Gated Sodium Channel -- genetics
- Seizures -- therapy
- Transcriptional Activation
- Treatment Outcome
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.